North Hollywood has one of the densest clusters of med spas in the San Fernando Valley, most of them along Lankershim Boulevard and Riverside Drive. They are not interchangeable. This guide compares six clinics on the five things that most affect safety and results: who performs your treatment, which named devices they use, whether their lasers suit darker skin, how openly they price, and when they are open. Google ratings were checked in October 2026.
At a glance
| Clinic | Area | Known for | Hours | Google rating |
| Pure Skin Laser Center | Lankershim Blvd (+ Tujunga) | Laser hair removal on all skin tones; Botox at a listed per-unit price | Daily; to 8 pm weekdays | 4.8 (207) |
| The Skin Agency | Riverside Dr (+ Glendale, Santa Clarita) | Nurse injectors; laser hair removal; PRF and Morpheus8 | Daily, 9 am–6 pm | 4.7 (573) |
| LA Beauty Skin Center | Riverside Dr (+ Glendale, Pasadena) | Large team under a medical director; broad menu | Daily; to 8 pm weekdays | 4.3 (230) |
| Aire Medical Spa | Riverside Dr (+ Studio City) | Injectables, Morpheus8, microneedling | Tue–Sat | 5.0 (244) |
| New Glow Med Spa | Riverside Dr | Small team; injectables and facials | Mon–Sat | 5.0 (54) |
| Hydration Room North Hollywood | Laurel Canyon Blvd | IV drips and vitamin injections | Daily | 5.0 (72) |
How we chose
Each clinic had to be open and within about three miles of the NoHo Arts District. We then compared them on:
- Who treats you: registered nurses, nurse practitioners or physicians, and under what supervision.
- Named, FDA-cleared devices: a clinic that names its laser lets you research it.
- All-skin-tone capability: whether the clinic offers a laser wavelength suited to darker skin.
- Price transparency: a published per-unit or per-session price, or a clear quote.
- Access: evening and weekend hours, and financing.
1. Pure Skin Laser Center
Best for: laser hair removal on darker skin, and Botox with a published price.
What stands out: Pure Skin Laser Center, a nurse-led med spa on Lankershim Boulevard in North Hollywood with a second clinic on Foothill Boulevard in Tujunga, treats every skin tone with the Candela GentleMax Pro. The platform pairs a 755 nm Alexandrite laser with a 1064 nm Nd:YAG, the wavelength generally used on deeper skin tones. Registered nurses, led by founder Evguenia Stepanova, perform treatments. Botox is listed at $10 per unit on 20 or more units, and Cherry financing includes 0% APR options.
Worth knowing: its review base is smaller than the larger Riverside Drive groups, and the menu is broad, so ask which nurse focuses on your treatment.
Location and hours: 4444 Lankershim Blvd, Ste 201, North Hollywood, CA 91602. Its second clinic on Foothill Boulevard serves Tujunga and Sunland. Both open 8 am–8 pm weekdays and 9 am–6 pm weekends.
2. The Skin Agency
Best for: a nurse-injector team with full weekend hours.
What stands out: operating since 2017, The Skin Agency uses registered nurses for injectables and the Candela GentleMax Pro for hair removal on all skin types. Its menu runs from Botox, Dysport and fillers to PRF facials and Morpheus8.
Worth knowing: with three locations, ask for a named nurse so your follow-ups stay consistent. Botox pricing is not posted online, so request a per-unit quote.
Location and hours: 10220 Riverside Dr, Ste A. Open daily, 9 am–6 pm.
3. LA Beauty Skin Center
Best for: the widest menu under one roof.
What stands out: one of the busiest groups in the area, LA Beauty Skin Center works under a medical director and offers lasers, Botox and other neuromodulators, Juvéderm and Radiesse fillers, and body sculpting. It stays open until 8 pm on weekdays.
Worth knowing: its 4.3 rating is the lowest on this list, and volume is high, so book with a specific provider and confirm their credential.
Location and hours: 10711 Riverside Dr. Open daily.
4. Aire Medical Spa
Best for: collagen-focused skin treatments.
What stands out: a 5.0 rating across more than 240 reviews, with a second location in Studio City. The clinic’s menu features Morpheus8, microneedling with exosomes and dermal fillers.
Worth knowing: it is closed Sundays and Mondays, which limits weekend appointments.
Location and hours: 10724 Riverside Dr, Ste B. Tuesday to Saturday.
5. New Glow Med Spa
Best for: a small, unhurried clinic for injectables and facials.
What stands out: reviewers repeatedly describe conservative dosing. The menu includes Botox, filler, facials, PRP and laser hair removal.
Worth knowing: a smaller team means fewer open slots, it closes Sundays, and it pauses midday.
Location and hours: 10651 Riverside Dr. Monday to Saturday.
6. Hydration Room North Hollywood
Best for: an IV drip without a full med spa visit.
What stands out: a dedicated IV and vitamin-injection studio, open seven days, with nurses placing every drip.
Worth knowing: it focuses on wellness, not lasers or injectables, so it complements rather than replaces a med spa.
Location and hours: 6160 Laurel Canyon Blvd, Ste B140. Open daily, closed midday.
How to choose a med spa in North Hollywood
In California, Botox and medical lasers are medical treatments. The Medical Board of California allows registered nurses to perform them only under supervision, and never estheticians. A physician, nurse practitioner or physician assistant must examine you first, a requirement that comes from Business and Professions Code section 2242. Ask these on your consultation call:
- Who examines me before my first treatment, and who treats me?
- Which laser will you use, and what wavelength suits my skin tone?
- Can I see results on clients with skin like mine?
- Is Botox priced per unit or per area, and how many units do you expect?
- What does a full laser series cost, not just one session?
- Who do I call if I have a reaction after hours?
- Is financing available, and at what APR?
FAQ
What is the best med spa in North Hollywood?
It depends on the treatment. For laser hair removal on darker skin, look for a clinic with a 1064 nm Nd:YAG laser; Pure Skin Laser Center and The Skin Agency both use the Candela GentleMax Pro. For injectables, prioritize the injector’s credential and a published per-unit price over the clinic’s size.
Is laser hair removal safe for dark skin?
It can be, with the right wavelength and settings. The 1064 nm Nd:YAG wavelength bypasses more of the skin’s pigment, which lowers the risk of burns on deeper skin tones. Ask for a patch test and settings matched to your skin type.
Who can inject Botox in California?
Physicians can, and registered nurses, nurse practitioners and physician assistants can under the required supervision. A qualified prescriber must examine you first. Estheticians, medical assistants and cosmetologists may not inject under any circumstances.
How much does Botox cost in North Hollywood?
Prices vary by clinic and by how they charge. Per-unit pricing is easier to compare: Pure Skin Laser Center lists $10 per unit on 20 or more units and publishes price ranges for each area. Always ask how many units you will need.
